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[1] Saggu, S., Bai, A., Aida, M., Rehman, H., Pless, A., Ware, D., De\u00e1k, F., Jiao, K., & Wang, Q. (2024). Monoamine alterations in Alzheimer\u2019s disease and their implications in comorbid neuropsychiatric symptoms. GeroScience<\/em>, 47, 457\u2013482. https:\/\/doi.org\/10.1007\/s11357-024-01359-x<\/p>\n\n\n\n[2] Gaikwad, S., Senapati, S., Haque, M. A., & Kayed, R. (2023). Senescence, brain inflammation, and oligomeric tau drive cognitive decline in Alzheimer’s disease: Evidence from clinical and preclinical studies. Alzheimer’s & Dementia<\/em>, 20, 709\u2013727. https:\/\/doi.org\/10.1002\/alz.13490<\/p>\n\n\n\n[3] van Olst, L., Kamermans, A., Halters, S., van der Pol, S. M. A., Rodriguez, E., Verberk, I., Verberk, S., Wessels, D. W. R., Rodriguez-Mogeda, C., Verhoeff, J., Wouters, D., Van den Bossche, J., Garcia-Vallejo, J., Lemstra, A., Witte, M., van der Flier, W. M., Teunissen, C., & de Vries, H. E. (2024). Adaptive immune changes associate with clinical progression of Alzheimer\u2019s disease. Molecular Neurodegeneration<\/em>, 19. https:\/\/doi.org\/10.1186\/s13024-024-00726-8<\/p>\n\n\n\n[4] Mahanta, A. K., Chaulagain, B., Trivedi, R., & Singh, J. (2024). Mannose-Functionalized Chitosan-Coated PLGA Nanoparticles for Brain-Targeted Codelivery of CBD and BDNF for the Treatment of Alzheimer’s Disease. ACS Chemical Neuroscience<\/em>. https:\/\/doi.org\/10.1021\/acschemneuro.4c00392<\/p>\n\n\n\n[5] Zheng, H. T., Wu, Z., Mielke, M. M., Murray, A., & Ryan, J. (2024). Plasma Biomarkers of Alzheimer\u2019s Disease and Neurodegeneration According to Sociodemographic Characteristics and Chronic Health Conditions. The Journal of Prevention of Alzheimer’s Disease<\/em>, 11, 1189\u20131197. https:\/\/doi.org\/10.14283\/jpad.2024.142<\/p>\n\n\n\n[6] Denning, A. E., Ittyerah, R., Levorse, L., Sadeghpour, N., Athalye, C., Chung, E.-B., Ravikumar, S., Dong, M., Duong, M., Li, Y., Ilesanmi, A., Sreepada, L. P., Sabatini, P., Lowe, M., Bahena, A., Zablah, J., Spencer, B. E., Watanabe, R., Kim, B., S\u00f8rensen, M. H., Khandelwal, P., Brown, C. A., Hrybouski, S., Xie, S. X., de Flores, R., Robinson, J., Schuck, T., Ohm, D., Arezoumandan, S., Porta, S., Detre, J. A., Insausti, R., Wisse, L., Das, S. R., Irwin, D. J., Lee, E. B., Wolk, D., & Yushkevich, P. (2024). Association of quantitative histopathology measurements with antemortem medial temporal lobe cortical thickness in the Alzheimer\u2019s disease continuum. Acta Neuropathologica<\/em>, 148. https:\/\/doi.org\/10.1007\/s00401-024-02789-9<\/p>\n\n\n\n[7] Jin, M., Ma, Z., Dang, R., Zhang, H., Kim, R., Xue, H., Pascual, J., Finkbeiner, S., Head, E., Liu, Y., & Jiang, P. (2024). A Trisomy 21-linked Hematopoietic Gene Variant in Microglia Confers Resilience in Human iPSC Models of Alzheimer\u2019s Disease. bioRxiv<\/em>. https:\/\/doi.org\/10.1101\/2024.03.12.584646<\/p>\n\n\n\n[8] Chen, Y.-H., Wang, Z.-B., Liu, X.-P., & Mao, Z.-Q. (2025). Cerebrospinal Fluid CCL25 as a Biomarker for Alzheimer’s Disease: Associations with Pathology, Neurodegeneration, and Cognitive Decline. Molecular Neurobiology<\/em>. https:\/\/doi.org\/10.1007\/s12035-025-05007-z<\/p>\n\n\n\n[9] Jamison, D., Kadamangudi, S., Tumurbaatar, B., Zhang, W.-R., Palmer, L., Kunkel, S., Kayed, R., Limon, A., & Taglialatela, G. (2025). Comparative analysis of brain-derived tau oligomer interactomes in Alzheimer’s disease, non-demented with Alzheimer’s neuropathology, and primary age-related tauopathy: Implications for neurodegeneration and cognitive resilience. Journal of Alzheimer’s Disease<\/em>, 106, 1486\u20131508. https:\/\/doi.org\/10.1177\/13872877251352382 \u200b<\/p>\n","protected":false},"excerpt":{"rendered":"\u963f\u5c14\u8328\u6d77\u9ed8\u75c5\uff08Alzheimer\u2019s disease, AD\uff09\u662f\u4e00\u79cd\u4ee5\u8fdb\u884c\u6027\u8ba4\u77e5\u529f\u80fd\u8870\u9000\u4e3a\u6838\u5fc3\u7279\u5f81\u7684\u795e\u7ecf\u9000\u884c\u6027\u75be\u75c5\uff0c\u5176\u4e3b\u8981\u75c5\u7406\u8868\u73b0\u4e3a\u6dc0\u7c89\u6837\u6591\u5757\u6c89\u79ef\u3001\u795e\u7ecf\u7ea4\u7ef4\u7f20\u7ed3\u5f62\u6210\u4ee5\u53ca\u5e7f\u6cdb\u7684\u7a81\u89e6\u4e22\u5931\u548c\u795e\u7ecf\u5143\u6b7b\u4ea1\u3002\u5c3d\u7ba1\u4f20\u7edf\u7814\u7a76\u591a\u805a\u7126\u4e8e\u4e59\u9170\u80c6\u78b1\u7cfb\u7edf\u7684\u635f\u4f24\u53ca\u5176\u5728\u8bb0\u5fc6\u969c\u788d\u4e2d\u7684\u6838\u5fc3\u4f5c\u7528\uff0c\u8fd1\u5e74\u6765\u8d8a\u6765\u8d8a\u591a\u7684\u8bc1\u636e\u8868\u660e\uff0c\u5355\u80fa\u7c7b\u795e\u7ecf\u9012\u8d28\u7cfb\u7edf\u7684\u7d0a\u4e71\uff0c\u7279\u522b\u662f\u591a\u5df4\u80fa\uff08dopamine, DA\uff09\u7cfb\u7edf\u7684\u529f\u80fd\u5931\u8c03\uff0c\u5728AD\u7684\u53d1\u751f\u53d1\u5c55\u8fc7\u7a0b\u4e2d\u626e\u6f14\u7740\u4e0d\u53ef\u5ffd\u89c6\u7684\u89d2\u8272\u3002<\/p>\n","protected":false},"author":1,"featured_media":1020,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[8],"tags":[13,14,15,16],"class_list":["post-1019","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-8","tag-13","tag-14","tag-15","tag-16"],"_links":{"self":[{"href":"https:\/\/www.versabot.cn\/blog\/index.php?rest_route=\/wp\/v2\/posts\/1019","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.versabot.cn\/blog\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.versabot.cn\/blog\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.versabot.cn\/blog\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.versabot.cn\/blog\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=1019"}],"version-history":[{"count":1,"href":"https:\/\/www.versabot.cn\/blog\/index.php?rest_route=\/wp\/v2\/posts\/1019\/revisions"}],"predecessor-version":[{"id":1021,"href":"https:\/\/www.versabot.cn\/blog\/index.php?rest_route=\/wp\/v2\/posts\/1019\/revisions\/1021"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.versabot.cn\/blog\/index.php?rest_route=\/wp\/v2\/media\/1020"}],"wp:attachment":[{"href":"https:\/\/www.versabot.cn\/blog\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=1019"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.versabot.cn\/blog\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=1019"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.versabot.cn\/blog\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=1019"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}